Which statement best describes monitoring requirements for amiodarone?

• A. It requires monitoring of TSH due to potential thyroid effects
• B. It requires no monitoring
• C. It requires monitoring of lipid profile
• D. It requires imaging every week

Answer: (A)

Amiodarone is rich in iodine and can disrupt thyroid hormone production and conversion, leading to either hypothyroidism or hyperthyroidism. Because these thyroid effects can develop gradually and may be silent, it’s essential to check thyroid function before starting amiodarone and to monitor thyroid-stimulating hormone (TSH) periodically during treatment. If TSH becomes abnormal, add free T4 and clinical assessment to guide management, which may involve adjusting the medication or treating the thyroid disturbance. Monitoring lipid panels isn’t routinely needed for amiodarone, and imaging every week isn’t indicated for ongoing monitoring.