What is an advantage of IGRA (QuantiFERON-TB Gold) over the tuberculin skin test?

• A. Ability to obtain results without a return visit
• B. It can distinguish latent from active TB
• C. It is less expensive
• D. It requires less blood volume

Answer: (A)

An IGRA’s main advantage is that it can be completed in one visit. The tuberculin skin test requires a return visit within 48–72 hours to read the induration; if the person doesn’t come back, the result is not available. With an IGRA, a blood sample is drawn during the initial visit and processed in the lab, so results are obtained without a second appointment. This reduces loss to follow-up and improves test completion rates. Additional notes: IGRA can be less affected by prior BCG vaccination, but the primary, most practical benefit in many settings is the single-visit workflow.