In unilateral adolescent gynaecomastia, which side is more commonly involved?

• A. Left side
• B. Right side
• C. Both sides equally
• D. The side is always right

Answer: (A)

Unilateral gynecomastia during adolescence is most often seen on the left side. This left-sided predominance is a pattern observed in clinical experience, though the exact reason isn’t fully understood. It likely reflects subtle, natural asymmetries in breast tissue development or receptor sensitivity, rather than a distinct disease process. Remember that pubertal gynecomastia is usually transient and benign, but persistent or atypical features warrant further evaluation. The right side is less commonly involved in unilateral cases, and while bilateral involvement can occur during puberty, the left-sided unilateral presentation remains the more frequent pattern.