In asymptomatic sarcoidosis, which organ should be examined yearly to detect extrapulmonary manifestations?

• A. Cardiac
• B. Renal
• C. Ocular
• D. Dermatologic

Answer: (C)

Sarcoidosis can involve many organs beyond the lungs, and some of these manifestations can be silent at first. The eyes are particularly important because ocular sarcoidosis often does not cause noticeable symptoms until vision is threatened. An annual ophthalmologic evaluation, including a slit-lamp exam and dilated fundus exam, helps detect silent inflammatory changes such as anterior uveitis or granulomatous involvement early. Early detection allows timely treatment to prevent vision loss and reduces the risk of complications like cataracts or glaucoma from treatment or disease itself. While other extrapulmonary sites like the heart or kidneys can also be affected, the eyes are routinely screened yearly because ocular involvement can be present without symptoms and has a direct impact on vision.